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Symbol
Name
ID

C3
complement component 3
MGI:88227

Phenotype annotations related to liver/biliary system

Darker colors indicate more annotations

Human Phenotypes	Hepatomegaly	Cholelithiasis	Pigment gallstones	Jaundice
Disease(s) Associated with C3	Hepatomegaly	Cholelithiasis	Pigment gallstones	Jaundice
paroxysmal nocturnal hemoglobinuria
sickle cell anemia

Mouse Phenotypes		focal hepatic necrosis	decreased hepatocyte proliferation	liver inflammation	abnormal liver morphology	decreased susceptibility to alcohol-induced hepatic steatosis	hepatic steatosis	abnormal liver physiology	impaired liver regeneration
Availability	Mouse Genotype	focal hepatic necrosis	decreased hepatocyte proliferation	liver inflammation	abnormal liver morphology		hepatic steatosis	abnormal liver physiology	impaired liver regeneration
	C3^tm1Crr/C3^tm1Crr
	C3^tm1Hrc/C3^tm1Hrc

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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